Allergy: Difference between revisions
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An allergy is any adverse (bad) reaction the body has to a substance that are normally considered harmless where [[IgE|IgE]] is involved <ref>Gamlin, Linda (2005). The Allergy Bible. London: Quadrille Limited. p6.</ref>. A substance which causes an [[Allergic reaction|allergic reaction]] is called an [[Allergen|allergen]]; they are said to be 'harmless' as they | An allergy is any adverse (bad) reaction the body has to a substance that are normally considered harmless where Immunglobulin E ([[IgE|IgE]]) is involved <ref>Gamlin, Linda (2005). The Allergy Bible. London: Quadrille Limited. p6.</ref>. A substance which causes an [[Allergic reaction|allergic reaction]] is called an [[Allergen|allergen]]; they are said to be 'harmless' as they only affect those who are allergic. An allergic reaction arises when the body fails to recognise the allergen as harmless and responds by producing [[Antibody|antibodies]] as part of an immune response. The anitobodies are made up of a [[Protein|protein]] called [[Immunoglobulin|immunoglobulin]], which exists in various forms within the body. IgE is the protein associated with allergic responses; elevated levels of IgE can be found (and tested for) in those who have suffered an allergic reaction. The allergy arises when the body comes into contact with the allergen for a second time, as during the first encounter [[Lymphocyte|lymphocyte]] cells make antibodies, so when the allergen enters the body a second time more antibodies attach themselves to mast cells located near the skin. The antibodies then bind to the allergen activating the mast cells, causing them to break and release [[Histamine|histamine]]. This results in the symptoms of an allergic reaction <ref>White, Dr.T. (1990). Living with Allergies. London: Franklin Watts Ltd.</ref>. <br> | ||
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Revision as of 16:03, 3 December 2015
An allergy is any adverse (bad) reaction the body has to a substance that are normally considered harmless where Immunglobulin E (IgE) is involved [1]. A substance which causes an allergic reaction is called an allergen; they are said to be 'harmless' as they only affect those who are allergic. An allergic reaction arises when the body fails to recognise the allergen as harmless and responds by producing antibodies as part of an immune response. The anitobodies are made up of a protein called immunoglobulin, which exists in various forms within the body. IgE is the protein associated with allergic responses; elevated levels of IgE can be found (and tested for) in those who have suffered an allergic reaction. The allergy arises when the body comes into contact with the allergen for a second time, as during the first encounter lymphocyte cells make antibodies, so when the allergen enters the body a second time more antibodies attach themselves to mast cells located near the skin. The antibodies then bind to the allergen activating the mast cells, causing them to break and release histamine. This results in the symptoms of an allergic reaction [2].
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