Holoenzyme: Difference between revisions

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Use of the same [[Coenzyme|coenzyme]] usually means that [[Enzyme|enzymes]] catalyse similar mechanisms&nbsp;<ref>Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman, p207</ref>.<br>  
Use of the same [[Coenzyme|coenzyme]] usually means that [[Enzyme|enzymes]] catalyse similar mechanisms&nbsp;<ref>Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman, p207</ref>.<br>  


=== '''References'''<br>  ===
=== sigma 70 and RNA polymerase II&nbsp;is an example of a holoenzyme used in transcription of prokaryotes. ===


<references /><br>
<ref>Bourbon HM, Aguilera A, Ansari AZ et al. (2004) A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell 14: 553–557</ref>
 
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Revision as of 10:27, 20 October 2017

Holoenzyme is a catalytically active enzyme that consists of apoenzyme and cofactor. Cofactors can make reactions that cannot be done by standard twenty amino acids. Cofactors are divided in two groups:

Use of the same coenzyme usually means that enzymes catalyse similar mechanisms [1].

sigma 70 and RNA polymerase II is an example of a holoenzyme used in transcription of prokaryotes.

[2]

  1. Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman, p207
  2. Bourbon HM, Aguilera A, Ansari AZ et al. (2004) A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell 14: 553–557