Holoenzyme: Difference between revisions
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Use of the same [[Coenzyme|coenzyme]] usually means that [[Enzyme|enzymes]] catalyse similar mechanisms <ref>Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman, p207</ref>.<br> | Use of the same [[Coenzyme|coenzyme]] usually means that [[Enzyme|enzymes]] catalyse similar mechanisms <ref>Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman, p207</ref>.<br> | ||
=== sigma 70 and RNA polymerase II is an example of a holoenzyme used in transcription of prokaryotes. === | === sigma 70 and RNA Polymerase II<ref>Bourbon HM, Aguilera A, Ansari AZ et al. (2004) A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Molecular Cell 14: 553–557.</ref> is an example of a holoenzyme used in transcription of prokaryotes. === | ||
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Revision as of 10:33, 20 October 2017
Holoenzyme is a catalytically active enzyme that consists of apoenzyme and cofactor. Cofactors can make reactions that cannot be done by standard twenty amino acids. Cofactors are divided in two groups:
Use of the same coenzyme usually means that enzymes catalyse similar mechanisms [1].
sigma 70 and RNA Polymerase II[2] is an example of a holoenzyme used in transcription of prokaryotes.