RNA polymerase: Difference between revisions
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RNA polymerase is an [[Enzyme|enzyme]] that catalyzes [[Transcription|transcription]] and produces [[RNA|RNA]]. Bacteria have a single type of RNA polymerase whereas [[Eukaryotes|eucaryotic]] nuclei have three, RNA polymerase I, RNA polymerase II and RNA polymerase III. It unwinds the [[DNA|DNA]] for complementary base-pairing in the 5' - 3' direction (downstream). The [[Nucleotide|nucleotides]] for base-pairing are UTP, ATP, GTP and CTP. The hydrolysis of the | RNA polymerase is an [[Enzyme|enzyme]] that catalyzes [[Transcription|transcription]] and produces [[RNA|RNA]]. Bacteria have a single type of RNA polymerase whereas [[Eukaryotes|eucaryotic]] nuclei have three, RNA polymerase I, RNA polymerase II and RNA polymerase III. It unwinds the [[DNA|DNA]] for complementary base-pairing in the 5' - 3' direction (downstream). The [[Nucleotide|nucleotides]] for base-pairing are UTP, ATP, GTP and CTP. The hydrolysis of the nucleotide triphosphate bonds gives energy for transcription to move forward. Unlike [[DNA replication|DNA replication]], transcription doesn't require RNA primers. However, RNA polymerase make about one mistake per 10<sup>4</sup> nulceotides, whereas DNA polymerase only makes about one mistake per 10<sup>7</sup> nucleotides<ref name="null">Alberts, B. et al., 2002. Molecular Biology of the Cell. Fourth Edition. New York: Garland Science.</ref>. | ||
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Revision as of 18:30, 28 November 2010
RNA polymerase is an enzyme that catalyzes transcription and produces RNA. Bacteria have a single type of RNA polymerase whereas eucaryotic nuclei have three, RNA polymerase I, RNA polymerase II and RNA polymerase III. It unwinds the DNA for complementary base-pairing in the 5' - 3' direction (downstream). The nucleotides for base-pairing are UTP, ATP, GTP and CTP. The hydrolysis of the nucleotide triphosphate bonds gives energy for transcription to move forward. Unlike DNA replication, transcription doesn't require RNA primers. However, RNA polymerase make about one mistake per 104 nulceotides, whereas DNA polymerase only makes about one mistake per 107 nucleotides[1].
References
- ↑ Alberts, B. et al., 2002. Molecular Biology of the Cell. Fourth Edition. New York: Garland Science.