T Lymphocytes: Difference between revisions
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Why did you remove all the links I added at 12:23, 20 October 2016? Added some links (again). |
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T-cells originate from [[ | T-cells originate from haematopoietic [[Stem cells|stem cells]] in the [[Bone marrow|bone marrow]] and migrate to the thymus to undergo maturation. The T-cell precursor rearranges its [[T-cell receptor genes|T-cell receptor genes]] in the [[Thymus|thymus]]. Immature T-cells that recognise self [[MHC Molecules|MHC]] then receive a signal for survival and cells that interact with cell [[Antigens|antigens]] are swiftly removed and destroyed, this process is known as positive and negative selection in the thymus. Mature T-cells are then able to encounter foreign [[Antigens|antigens]] presented by MHC molecules in the peripheral lymphoid organs where the cells are then activated and can proliferate and destroy the organism. | ||
Revision as of 14:12, 22 October 2018
T-cells originate from haematopoietic stem cells in the bone marrow and migrate to the thymus to undergo maturation. The T-cell precursor rearranges its T-cell receptor genes in the thymus. Immature T-cells that recognise self MHC then receive a signal for survival and cells that interact with cell antigens are swiftly removed and destroyed, this process is known as positive and negative selection in the thymus. Mature T-cells are then able to encounter foreign antigens presented by MHC molecules in the peripheral lymphoid organs where the cells are then activated and can proliferate and destroy the organism.