Deacetylation: Difference between revisions

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=== Gene Trancription Repression  ===
=== Gene Trancription Repression  ===


[[Histone Deacetylases|Histone Deacetylases]] (HDAC) are [[chromatin|chromatin]] modifying factor. HDAC can remove acetyl from [[histone|histone]] to allow [[DNA|DNA]] to wrap more tightly to prevent [[transcription|transcription]]<ref>Sumana C, Salil SP, Swati M, Nitin K, Karisetty BC, Arvind K. Chapter Four - Epigenetic Regulatory Mechanisms in Stress-Induced Behavior, fckLRInternational Review of Neurobiology. 2014:115:117-154.</ref>.
[[Histone Deacetylases|Histone Deacetylases]] (HDAC) are [[Chromatin|chromatin]] modifying factor. HDAC can remove acetyl from [[Histone|histone]] to allow [[DNA|DNA]] to wrap more tightly to prevent [[Transcription|transcription]]<ref>Sumana C, Salil SP, Swati M, Nitin K, Karisetty BC, Arvind K. Chapter Four - Epigenetic Regulatory Mechanisms in Stress-Induced Behavior, fckLRInternational Review of Neurobiology. 2014:115:117-154.</ref>. Deacetylation is caused by HDAC via hydrolosis.&nbsp;


=== References  ===
=== References  ===


<references />
<references />

Latest revision as of 13:51, 26 October 2018

Deacetylation is the process which acetyl group is removed from chemical compound.

Gene Trancription Repression

Histone Deacetylases (HDAC) are chromatin modifying factor. HDAC can remove acetyl from histone to allow DNA to wrap more tightly to prevent transcription[1]. Deacetylation is caused by HDAC via hydrolosis. 

References

  1. Sumana C, Salil SP, Swati M, Nitin K, Karisetty BC, Arvind K. Chapter Four - Epigenetic Regulatory Mechanisms in Stress-Induced Behavior, fckLRInternational Review of Neurobiology. 2014:115:117-154.