Promoters: Difference between revisions
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The DNA region or sequence that helps in initiating | The [[DNA|DNA]] region or sequence that helps in initiating [[transcription|transcription]] is known as the promoter. [[RNA polymerase|RNA polymerase]] binds to the promoter and further initiates transcription of a [[gene|gene]]. | ||
Core/Basal elements include TATA boxes and Initiator Sequences (Inr). CpG islands are also present in mammals. | They can be present close to the [[transcription start site|transcription start site]] or many kilobases away. | ||
Based on their location they can be characterised as Core/[[Basal Promoter Element|Basal Promoter Elements]] or the [[Regulatory Region Element|Regulatory Region Elements]]. | |||
Core/Basal elements include [[TATA_box|TATA boxes]] and [[Initiator Sequence|Initiator Sequences]] (Inr). [[CpG_island|CpG islands]] are also present in [[mammals|mammals]]. | |||
Regulatory region elements include UAS/enhancer elements and URS/silencer elements. | |||
Other promoters are Downstream Promoter elements (DPE) and BRE (TFIIB recognition element). | |||
Latest revision as of 16:49, 3 November 2018
The DNA region or sequence that helps in initiating transcription is known as the promoter. RNA polymerase binds to the promoter and further initiates transcription of a gene.
They can be present close to the transcription start site or many kilobases away.
Based on their location they can be characterised as Core/Basal Promoter Elements or the Regulatory Region Elements.
Core/Basal elements include TATA boxes and Initiator Sequences (Inr). CpG islands are also present in mammals.
Regulatory region elements include UAS/enhancer elements and URS/silencer elements.
Other promoters are Downstream Promoter elements (DPE) and BRE (TFIIB recognition element).