Nucleosides: Difference between revisions
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Nucleosides consist of a sugar ([[ | Nucleosides consist of a sugar ([[Ribose|ribose]] or [[Deoxyribose|deoxyribose]]) and a [[Base|heterocyclic base]] joined by a [[Glycosidic bond|glycosidic bond]]. A nucleoside with a [[Ribose|ribose sugar]] would be known as a ribonucleoside and a nucleoside with a [[Deoxyribose sugar|deoxyribose sugar]] is known as a [[Deoxyribonucleoside|deoxyribonucleoside]]<ref>http://www.biology-online.org/dictionary/Nucleoside</ref>. [[Nucleic acid|Nucleic acid]] can be hydrolysed to produce nucelosides. Nucleosides can be [[Phosphorylation|phosphorylated]] by [[Kinase|kinases]] to produce [[Nucleotides|nucleotides]]. | ||
Nucleoside triphospates are nucleosides with 3 [[Phosphate group|phosphate groups]] attached, these are used by [[DNA Primase|DNA primase to]] synthesize [[RNA primer|RNA primers]] on the lagging strand during [[DNA replication|DNA replication]] | Nucleoside triphospates are nucleosides with 3 [[Phosphate group|phosphate groups]] attached, these are used by [[DNA Primase|DNA primase to]] synthesize [[RNA primer|RNA primers]] on the lagging strand during [[DNA replication|DNA replication]]<ref>Alberts B., Johnson A., Lewis J., Raff M., Roberts K. and Walson J. (2007) Molecular Biology of the Cell, New York: Garland. Page 268</ref> ([[ATP|ATP]], [[CTP|CTP]], [[UTP|UTP]] and [[GTP|GTP]]). | ||
The difference between a nucleoside and a nucleotide is that a nucleotide contains a phospate group.<br> | The difference between a nucleoside and a nucleotide is that a nucleotide contains a phospate group.<br> | ||
Latest revision as of 14:34, 2 December 2018
Nucleosides consist of a sugar (ribose or deoxyribose) and a heterocyclic base joined by a glycosidic bond. A nucleoside with a ribose sugar would be known as a ribonucleoside and a nucleoside with a deoxyribose sugar is known as a deoxyribonucleoside[1]. Nucleic acid can be hydrolysed to produce nucelosides. Nucleosides can be phosphorylated by kinases to produce nucleotides.
Nucleoside triphospates are nucleosides with 3 phosphate groups attached, these are used by DNA primase to synthesize RNA primers on the lagging strand during DNA replication[2] (ATP, CTP, UTP and GTP).
The difference between a nucleoside and a nucleotide is that a nucleotide contains a phospate group.
References
- ↑ http://www.biology-online.org/dictionary/Nucleoside
- ↑ Alberts B., Johnson A., Lewis J., Raff M., Roberts K. and Walson J. (2007) Molecular Biology of the Cell, New York: Garland. Page 268