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Immunoglobulin G (IgG) is an antibody, which is abundant in the blood, lumph and extracellular fluid | [[Immunoglobulin|Immunoglobulin]] G (IgG) is an [[Antibody|antibody]], which is abundant in the [[Blood|blood]], lumph and extracellular fluid <ref>Parham,P. (2009) The Imuune System, 3rd edition, New York, Garland Science</ref>. | ||
IgG plays various roles in the immune response, but primarily , it aids the phagocytosis of pathogens and alleviates their destruction | IgG plays various roles in the [[immune response|immune response]], but primarily , it aids the phagocytosis of [[pathogen|pathogens]] and alleviates their destruction <ref>Parham, P. (2009)The Immune System, 3rd edition, New York, Garland Science</ref>. IgG acts by coating the [[microorganism|microorganism]], a process known as 'opsonization' and then binds to [[Phagocytes|phagocytes]] through its constant regions. Being coated by the IgG, the pathogen is captured by the [[neutrophil|neutrophils]] and the [[Macrophage|macrophages]] and finally undergoes destruction by the latter <ref>Parham, P. (2009)The Immune System, 3rd edition, New York, Garland Science</ref>. | ||
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Revision as of 14:20, 15 November 2011
Immunoglobulin G (IgG) is an antibody, which is abundant in the blood, lumph and extracellular fluid [1].
IgG plays various roles in the immune response, but primarily , it aids the phagocytosis of pathogens and alleviates their destruction [2]. IgG acts by coating the microorganism, a process known as 'opsonization' and then binds to phagocytes through its constant regions. Being coated by the IgG, the pathogen is captured by the neutrophils and the macrophages and finally undergoes destruction by the latter [3].