Initiation of DNA Replication: Difference between revisions

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*Generation of a primer which can be extended with the help of [[DNA polymerase]] by adding nucleotides. 
*Generation of a primer which can be extended with the help of [[DNA polymerase]] by adding nucleotides. 


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Revision as of 13:46, 25 November 2011

DNA replication is initiated from fixed origins which includes repeated sequences. [1] For initiation of replication, two things are essential:

  • A Nucleotide sequence that binds to initiation proteins.
  • Generation of a primer which can be extended with the help of DNA polymerase by adding nucleotides. 

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  1. Mathews et al. 2000. Biochemistry. 3rd Edition. Benjamin Cummings. Pg 909.