Autosomal Dominant Disorders: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
An [https://bms.ncl.ac.uk/wiki/index.php/Autosome autosomal] [[Dominant|dominant]] disorder is a genetically inheritable disorder which the offspring of the affected individuals will show the [[Phenotype|phenotype]] of the disorder whether they are [[Homozygous|homozygous]] dominant or [[Heterozygous|heterozygous]]. In this kind of disorder, the dominant allele carries the defect while the recessive allele is the normal allele and the dominance relationship results in the individual to show the observable defect.<br> | An [https://bms.ncl.ac.uk/wiki/index.php/Autosome autosomal] [[Dominant|dominant]] disorder is a genetically inheritable disorder which the offspring of the affected individuals will show the [[Phenotype|phenotype]] of the disorder whether they are [[Homozygous|homozygous]] dominant or [[Heterozygous|heterozygous]]. In this kind of disorder, the dominant allele carries the defect while the recessive allele is the normal allele and the dominance relationship results in the individual to show the observable defect.<br> | ||
The pedigree analysis for this particular disorder shows the phenotype of the defect in each generation due to the dominance relationship with equal chances of passing the defect to both males and females offspring. | The pedigree analysis for this particular disorder shows the phenotype of the defect in each generation due to the dominance relationship with equal chances of passing the defect to both males and females offspring. | ||
Example of autosomal dominant disorders are Pseudoachondroplasia, Huntington disease, Polydactyly and etc. | Example of autosomal dominant disorders are Pseudoachondroplasia, Huntington disease, Polydactyly and etc.<ref>Griffths A. J. F., Wessler S. R., Lewontin R. C., Carroll S. B. (2008) Introduction to Genetic Analysis. 9th Edition. New York: W. H. Freeman and Company</ref><references /> | ||
Revision as of 11:23, 2 December 2011
An autosomal dominant disorder is a genetically inheritable disorder which the offspring of the affected individuals will show the phenotype of the disorder whether they are homozygous dominant or heterozygous. In this kind of disorder, the dominant allele carries the defect while the recessive allele is the normal allele and the dominance relationship results in the individual to show the observable defect.
The pedigree analysis for this particular disorder shows the phenotype of the defect in each generation due to the dominance relationship with equal chances of passing the defect to both males and females offspring.
Example of autosomal dominant disorders are Pseudoachondroplasia, Huntington disease, Polydactyly and etc.[1]
- ↑ Griffths A. J. F., Wessler S. R., Lewontin R. C., Carroll S. B. (2008) Introduction to Genetic Analysis. 9th Edition. New York: W. H. Freeman and Company