Paracetamol: Difference between revisions
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Paracetamol is a Non-Steroidal AntiInflammatory Drug (NSAID) which is commonly used as an analgesic | Paracetamol is a [[Non-Steroidal AntiInflammatory Drug|Non-Steroidal AntiInflammatory Drug]] (NSAID) which is commonly used as an [[analgesic|analgesic]] <ref>Rang H.P, Dale M.M, Ritter J.M Flower R.J, Henderson G, (2012) Rang and Dale's Pharmacology, Seventh Edition, Philadelphia, Elsevier Limited, 320</ref>. | ||
Paracetamol works by inhibiting the function of arachidonic acid cyclo-oxygenase (COX), which results in the decrease in prostanoid synthesis, e.g. Prostacyclin and PGE2. These compounds are inflammatory mediators thus decrease in the synthesis of these products cause the anti-inflammatory effects | Paracetamol works by inhibiting the function of [[arachidonic acid cyclo-oxygenase|arachidonic acid cyclo-oxygenase]] (COX), which results in the decrease in [[prostanoid synthesis|prostanoid synthesis]], e.g. [[Prostacyclin|Prostacyclin]] and [[PGE2|PGE2]]. These compounds are inflammatory mediators thus decrease in the synthesis of these products cause the [[ANTI-INFLAMMATORY_DRUGS|anti-inflammatory]] effects <ref>Rang H.P, Dale M.M, Ritter J.M Flower R.J, Henderson G, (2012) Rang and Dale's Pharmacology, Seventh Edition, Philadelphia, Elsevier Limited, 320</ref>. | ||
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Revision as of 21:34, 21 October 2012
Paracetamol is a Non-Steroidal AntiInflammatory Drug (NSAID) which is commonly used as an analgesic [1].
Paracetamol works by inhibiting the function of arachidonic acid cyclo-oxygenase (COX), which results in the decrease in prostanoid synthesis, e.g. Prostacyclin and PGE2. These compounds are inflammatory mediators thus decrease in the synthesis of these products cause the anti-inflammatory effects [2].