Prostacyclin

Prostacyclin (also called PGI₂) is a prostaglandin belonging to the eicosanoid family^[1], produced by intact vascular endothelial cells^[2]. When prostacyclin is produced, it prevents platelet adhesion and aggregation so that clots are not unintentionally formed within blood vessels^[3]. When the endothelium lining blood vessels is damaged, prostacyclin production is stopped and platelet aggregation occurs, allowing a clot to form and seal the break^[4]. Prostacyclin is also a vasodilator^[5].

References

↑ https://en.wikipedia.org/wiki/Prostacyclin
↑ Silverthorn U.D., Johnson B.R., Ober W.C., Garrison C.W., Silverthorn A.C., 'Human Physiology: An Integrated Approach', 6th Edition, Pearson Education, 2013
↑ Silverthorn U.D., Johnson B.R., Ober W.C., Garrison C.W., Silverthorn A.C., 'Human Physiology: An Integrated Approach', 6th Edition, Pearson Education, 2013
↑ Silverthorn U.D., Johnson B.R., Ober W.C., Garrison C.W., Silverthorn A.C., 'Human Physiology: An Integrated Approach', 6th Edition, Pearson Education, 2013
↑ Silverthorn U.D., Johnson B.R., Ober W.C., Garrison C.W., Silverthorn A.C., 'Human Physiology: An Integrated Approach', 6th Edition, Pearson Education, 2013

[1] ttps://en.wikipedia.org/wiki/Prostacyclin

[2] Silverthorn U.D., Johnson B.R., Ober W.C., Garrison C.W., Silverthorn A.C., 'Human Physiology: An Integrated Approach', 6th Edition, Pearson Education, 2013

[3] Silverthorn U.D., Johnson B.R., Ober W.C., Garrison C.W., Silverthorn A.C., 'Human Physiology: An Integrated Approach', 6th Edition, Pearson Education, 2013

[4] Silverthorn U.D., Johnson B.R., Ober W.C., Garrison C.W., Silverthorn A.C., 'Human Physiology: An Integrated Approach', 6th Edition, Pearson Education, 2013

[5] Silverthorn U.D., Johnson B.R., Ober W.C., Garrison C.W., Silverthorn A.C., 'Human Physiology: An Integrated Approach', 6th Edition, Pearson Education, 2013

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Prostacyclin

References

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