Replication fork: Difference between revisions
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The Replication Fork is the site from which [[DNA|DNA]] is [[DNA synthesis|synthesised]]. As the new strands are formed from the parental strand as it unwinds, it forms a fork shape <ref>Berg J., Tymoczko J and Stryer L. (2012) Biochemistry, 7th edition, New York: WH Freeman.fckLRPage 853</ref>. At a replication fork, both strands are synthesised in a 5' to 3' direction. The leading strand is synthesised continuously, whereas the lagging strand is synthesised in short pieces called Okazaki fragments | The Replication Fork is the site from which [[DNA|DNA]] is [[DNA synthesis|synthesised]]. As the new strands are formed from the parental strand as it unwinds, it forms a fork shape <ref>Berg J., Tymoczko J and Stryer L. (2012) Biochemistry, 7th edition, New York: WH Freeman.fckLRPage 853</ref>. At a replication fork, both strands are synthesised in a 5' to 3' direction. The leading strand is synthesised continuously, whereas the lagging strand is synthesised in short pieces called [[Okazaki fragments|Okazaki fragments]]<ref>Stryer, Biochemistry 5th Edition, 760</ref>. | ||
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Revision as of 16:30, 30 November 2012
The Replication Fork is the site from which DNA is synthesised. As the new strands are formed from the parental strand as it unwinds, it forms a fork shape [1]. At a replication fork, both strands are synthesised in a 5' to 3' direction. The leading strand is synthesised continuously, whereas the lagging strand is synthesised in short pieces called Okazaki fragments[2].
Reference