Holoenzyme: Difference between revisions

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Holoenzyme is a catalytically active [[Enzyme|enzyme]] that consists of [[Apoenzyme|apoenzyme]] and [[Cofactor|cofactor]]. [[Cofactor|Cofactors]] can make reactions that cannot be done by standard twenty [[Amino acids|amino acids]]. [[Cofactors|Cofactors]] are divided in two groups:<br>  
Holoenzyme is a catalytically active [[Enzyme|enzyme]] that consists of [[Apoenzyme|apoenzyme]] and [[Cofactor|cofactor]]. [[Cofactor|Cofactors]] can make reactions that cannot be done by standard twenty [[Amino acids|amino acids]]. [[Cofactors|Cofactors]] are divided in two groups:<br>  


*metals ([[Zinc|Zn]]<sup>[[Zinc|2+]]</sup>, [[Magnesium|Mg]]<sup>[[Magnesium|2+]]</sup>, [[Nickel|Ni]]<sup>[[Nickel|2+]]</sup> , [[Molybdenum|Mo]], [[Selenium|Se]], [[Manganese|Mn]], [[Potassium|K]]<sup>[[Potassium|+]]</sup>),<br>  
*[[Metal Ions|metals]] ([[Zinc|Zn]]<sup>[[Zinc|2+]]</sup>, [[Magnesium|Mg]]<sup>[[Magnesium|2+]]</sup>, [[Nickel|Ni]]<sup>[[Nickel|2+]]</sup> , [[Molybdenum|Mo]], [[Selenium|Se]], [[Manganese|Mn]], [[Potassium|K]]<sup>[[Potassium|+]]</sup>),<br>  
*[[Coenzyme|coenzymes]].
*[[Coenzyme|coenzymes]].



Revision as of 01:12, 21 October 2013

Holoenzyme is a catalytically active enzyme that consists of apoenzyme and cofactor. Cofactors can make reactions that cannot be done by standard twenty amino acids. Cofactors are divided in two groups:

Use of the same coenzyme usually means that enzymes catalyse similar mechanisms [1].

References

  1. Berg J., Tymoczko J and Stryer L. (2007) Biochemistry, 6th edition, New York: WH Freeman, p207