Chromatin: Difference between revisions
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A complex of [[DNA|DNA]], [[ | A complex of [[DNA|DNA]], [[Histones|histones]] and [[Non-histone chromosomal proteins|nonhistone chromosomal proteins]], which condense to make up the [[Chromosomes|chromosomes]] found in [[Eukaryote|eukaryotic]] [[Nucleus|nuclei]] <ref>Alberts, B. et al., 2007. Molecular Biology of the Cell. 5th ed. s.l.:Garland Science. p.G:7</ref>. 145 [[Base pair|bp]] of DNA is wound into a left-handed superhelix <ref>Berg, Jeremy M., et al. 2011. Biochemistry. 7th Edition. Palgrave MacMillan. p.976</ref> around 8 [[Histones|histones]] with up to 80 bp linking to the next "bead on a string". Each of these repeating units is a [[Nucleosome|nucleosome]].<br> | ||
Chromatin is formed to strengthen the DNA and decrease it's volume in the [[Cell|cell]], thus preventing damage. | Chromatin is formed to strengthen the DNA and decrease it's volume in the [[Cell|cell]], thus preventing damage. | ||
Revision as of 11:32, 21 October 2013
A complex of DNA, histones and nonhistone chromosomal proteins, which condense to make up the chromosomes found in eukaryotic nuclei [1]. 145 bp of DNA is wound into a left-handed superhelix [2] around 8 histones with up to 80 bp linking to the next "bead on a string". Each of these repeating units is a nucleosome.
Chromatin is formed to strengthen the DNA and decrease it's volume in the cell, thus preventing damage.