Ligation

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Ligation, in molecular biology, is the process where either 2 DNA or RNA strands are joined together by an enzyme called ligase. Ligation occurs during the cloning of DNA or during processes such as transformation of a plasmid. Ligation is important in biotechnology as it can allow for the detection and determination of changes in RNA sequences.[1]

  1. Nilsson et al (2001) "RNA-templated DNA ligation for transcript analysis" Nucleic acid research.