Centrosome

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A centrosome is a region in the cytosplasm of a cell in close proximity to a nucleus [1]. Within the centrosome are contained a pair of centrioles which play an essential role in the formation of the mitoitic spindle during replication of DNA (Deoxyribose Nucleic Acid).

Every centrosome consists of pericentriolar matrix, which envelopes the centrioles found in the centrosome [2]. From the matrix, an array of microtubules form the mitotic spindle at the correct stage during cell division.

In the majority of eukaryotic cells, duplication of the centrosome starts in the later stages of G1 and is completed during the systhesis stages of mitosis [3].

References

  1. Hartl et al. 2006, Essential Genetics p460, 4th edition : Jones and Bartlett Publishers
  2. Alberts et al. 2008, Molecular Biology of the Cell p1076, 5th edition, New York : Garland Science
  3. Hartl et al. 2006, Essential Genetics p460, 4th edition : Jones and Bartlett Publishers