Isocitrate dehydrogenase

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In the citric acid cycle, isocitrate dehydrogenase is the enzyme that catalyses the oxidation of isocitrate to oxalosuccinate, which is the unstable intermediate of the reaction; the end product (a-ketoglutaratre) is formed after CO2 is released.


Alberts, B. 2013. Essential cell biology. New York, NY: Garland Science