In the citric acid cycle, isocitrate dehydrogenase is the enzyme that catalyses the oxidation of isocitrate to oxalosuccinate, which is the unstable intermediate of the reaction; the end product (alpha-ketoglutaratre) is formed after CO2 is released.
- ↑ Alberts, B. 2013. Essential cell biology. New York, NY: Garland Science