Transmembrane

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A transmembrane protein is a protein which is associated with the lipid bilayer in the membrane. The protein runs right through the membrane with both cytosolic and extracellular domains. Transmembrane proteins are amphipathic; the hydrophobic regions interact with lipid tails inside the lipid bilayer and the hydrophillic regions are exposed [1].

References

  1. Alberts,B., Johnson,A., Lewis,J., Raff,M., Roberts,K. and Walter,P. (2008) Molecular Biology of the Cell, 5th Edition, 630