Adrenegic receptor

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Adrenergic receptors respond to adrenaline and noradrenaline and can be found in a variety of different tissues.

Adrenergic receptors can be subdivided into two major classes: α- and β-adrenoreceptors.

For α-adrenoreceptors, the potency and affinity is noradrenaline ≥ adrenaline >> isoprenaline.

For β-adrenoreceptors, the potency and affinity is isoprenaline > adrenaline > noradrenaline.

α-Adrenoreceptors are subdivided into two subgroups, α1 and α2 receptors.

β-Adrenoreceptors are subdivided into two subgroups, β1 and β2 receptors.

Adrenergic receptors are G-protein coupled receptors. [1]

References

  1. Gomparts,B.D (2009) 'signal transduction' (pp 38) Elsevier/academic press: Amsterdam.