Enzyme-substrate complex
Enzyme-Substrate (ES) complexes are formed during enzyme catalysed chemical reactions.
Every enzyme is equipt with a 'cleft' in its structure, which is complementary to a particular substrate. This is known as the active site. As well as shape, the specificity of the active site is developed further via the amino acid R-Groups within the site. These groups will interact specifically with the substrate molecule(s) [1]. The ES complex is the state in, which the active site of the enzyme is non-covalently bound to the substrate molecule(s). This is where the chemical reaction occurs.
ENZYME + SUBSTRATE -> ENZYME SUBSTRATE COMPLEX -> ENZYME + PRODUCT
The following is a useful video demonstrating the formation of an Enzyme Substrate Complex: www.youtube.com/watch
References
- ↑ https://docs.google.com/viewer?a=v&q=cache:Tn0x9PalpIkJ:www.biog1105-1106.org/demos/105/unit3/media/enzymes.pdf+enzyme+substrate+complex&hl=en&gl=uk&pid=bl&srcid=ADGEESinQz_Nw7C9lQYmplfliEswGAdvSyRx0aqr91j0UUF_y51PABTPgupe6supWcqudck5HgOKFbgnmCU-1rzngFubqzwP8zOZWQoUlM5Yxc3x0R_eMQMYqT7BxkkSqnb5M22ygi3f&sig=AHIEtbSTALob3Xfcnm8CLj2rhZKL97OWwA