Glut 4

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Glut4 is a member of the Solute Carrier Family 2 (SLCA2) and encodes a protein which is involved in the trafficking of glucose to the plasma membrane. The protein is crucial to glucose transport and mutations within the protein can be involved in Non-Insulin Dependent Diabetes Mellitus (Diabetes) [1].

In Diabetes, Glut4 mRNA and protein levels decreases in both white and brown adipose tissue. [2]

References

  1. ↑ Bogen JS Aug 2010 http://www.ncbi.nlm.nih.gov/pubmed/20417083
  2. ↑ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1130854/


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