Initiation of DNA Replication

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DNA replication is initiated from fixed origins which includes repeated sequences. For initiation of replication, two things are essential:

A Nucleotide sequence that binds to initiation proteins.

Generation of a primer which can be extended with the help of DNA polymerase by adding nucleotides ^[1].

References

↑ Mathews et al. 2000. Biochemistry. 3rd Edition. Benjamin Cummings. Pg 909.

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