Nonsense mutation

Nonsense mutation is when there is a nucleotide substitution causing a different amino acid to be coded for, which creates a stop codon . This causes the protein that is being encoded for to be truncated due to the premature termination of translation. ^[1]

References

^[1] Hartl, D. and Jones, E. (2009) Genetics: Genes and Genomes, U.S.A: Jones and Bartlett, page 515