Dna ligase

From The School of Biomedical Sciences Wiki
Revision as of 16:59, 20 October 2012 by 110505545 (talk | contribs)
Jump to navigation Jump to search

DNA ligase is an enzyme which serves as a catalyst. It works by repairing breaks in the sugar phosphate backbone in DNA by creating a bond between adjoining nucleotides[1].
In eukaryotes DNA ligase I family members play the major role[2].

References

  1. Mosby's Medical Dictionary, 8th edition. 2009, Elsevier.
  2. http://www.ncbi.nlm.nih.gov/pubmed/22918593