Transversion

A transversion is a type of gentic mutation which involves a substitution of a single nucleotide in a strand of DNA. This subsequently leads to a mismatched base pair. A transversion involves replacing a pyramidine for a purine or a purine for a pyramidine. A pyramidine is T (thymine) or C (cytosine). A purine is A (adenine) or G (guanine). Pyramidine to purine transversions are T to A, T to G, C to A or C to G. Possible purine to pyramidine transversions are A to T, A to C, G to T or G to C. In total there are eight possible different transversion substitiutions. Hartl, & Jones et al., 2012.