Histones
In order for DNA to be packaged tightly enough to fit into a chromosome, it wraps around proteins called Histones, located in the nucleus of a cell[1].
Histones can be organized into six classes:
- H1
- H2A
- H2B
- H3
- H4
- Archael
Without histones, DNA would be too long to fit within the nucleus.
Some other functions of histones include acetlyation, methylation, ubiquitination, and phosphorylation [2].