Leptin

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Leptin is a protein hormone produced by the body's adipose cells that provides a vital role in regulating energy balance. [1]  The concentration of leptin found is dependent on the total amount body fat, thus differing between individuals. It works by inhibiting hunger by sending signals to the hypothalamus[2]

Leptin is a 16kDA adipose-derived cytokine protein which consists of 167 amino acids. This protein is coded by the ob gene on chromosome 7.


References

  1. Klok MD1, Jakobsdottir S, Drent ML.The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review. 2007 Jan. Available from: https://www.ncbi.nlm.nih.gov/pubmed/17212793
  2. Hormone Health Network. What does Leptin do? 2016. Available from: http://www.hormone.org/hormones-and-health/what-do-hormones-do/cortisol/leptin