Islet Amyloidosis

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Human islet amyloid polypeptide or amylin (hA) is a 37-amino acid peptide hormone produced and co-secreted with insulin by pancreatic β-cells. Under physiological conditions, hA regulates a broad range of biological processes including insulin release and slowing of gastric emptying, thereby maintaining glucose homeostasis[1].

  1. Handb Exp Pharmacol. 2017 Oct 18. doi: 10.1007/164_2017_62.