Hippocampal synaptic plasticity
Hippocampal synaptic plasticity is the relationship between the neuronal memory and cellular mechanisms and synaptic plasticity of the hippocampus[1]. There are studies present which indicate that suggest hippocampal functions are important for higher cognitive function (e.g. impairment leads to cognitive problems in Huntington's)[2]. However, approaches are being brought in to help repair and improve damage to hippocampal synaptic plasticity - for example, Leptin-deficient mice have shown to have impaired hippocampal synaptic plasticity. Increasing Leptin levels made long-term potentiation possible and improved the memory of the deficient mice[3].