Tumour suppressor gene

Tumour Suppressor genes repair mistakes made in the DNA sequence, suppress the rate of cell division and if unable to repair damage, can cause programmed cell death (apoptosis) to prevent unwanted uncontrollable division (cancer). An example is the P53 gene which is involved in cell cycle regulation and apoptosis with the observed tumour types: brain tumours, sarcomas, leukaemia, breast cancer.