Penicillin

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Penicillin was the first antibiotic to be discovered. It permanently inactivates the key enzymes in bacterial cell walls [1].

It was in 1928 that Alexander Flemming first noted the effect of penicillium on the growth of staphyloccoci; yet it wasn't until 1941 that it was first used for treatment against bacterial infection.

References

  1. Berg JM, Tymoczko JL and Stryer L, 2007, Biochemistry 6th edition, NY, W. H Freeman and Company, page 109