Arachidonic acid

From The School of Biomedical Sciences Wiki
Jump to: navigation, search

Arachidonic acid is used for the creation of 2 essential unstaurated carboxylic acids, prostaglandins (PGE2) and Leukotrienes (LTB) through lipoxygenase-catalysed pathways[1].

Prostoglandins and Leukotrienes are prostanoids that function as local hormone agents and these are enzymatically derived from arachidonic acid. As both leukotrienes and prostaglandins are vital in tissue response after injury, arachidonic acid can be utilised for drug action[2].

Reference

  1. Rang, H., Ritter, J., Flower, R., Henderson, G. and Dale, M. (2016). Rang and Dale's pharmacology. [Edinburgh etc.]: Elsevier, Churchill Livingstone. Chapter 17, Page 218.
  2. Rang, H., Ritter, J., Flower, R., Henderson, G. and Dale, M. (2016). Rang and Dale's pharmacology. [Edinburgh etc.]: Elsevier, Churchill Livingstone. Chapter 17, Page 219.
Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox