Dystrophin

From The School of Biomedical Sciences Wiki
Jump to: navigation, search

Dystrophin is a very large protein, in fact the gene that encodes it, also called dystophin, is the greatest in size within the human body [1]. The protein plays an important role in muscle cohesion both in myogenic and skeletal muscle. It does so by forming a group with other proteins, otherwise known as a protein complex, which is involved in connecting the cytoskeleton of the muscle cells to one another. This aids the muscles' strength right down to individual muscle fibres and allows for contraction and relaxation of muscles without such movement would not be possible [2].

Diseases associated with abnormal dystrophin

References

  1. [Online Mendelian Inheritance in Man (1966-2015) "MUSCULAR DYSTROPHY, DUCHENNE TYPE; DMD" Available at:http://omim.org/entry/310200?search=duchenne%20muscular%20dystrophy&highlight=duchenne%20dystrophy%20muscular. Last accessed 22/10/2015]
  2. [Online Mendelian Inheritance in Man (1966-2015) "MUSCULAR DYSTROPHY, DUCHENNE TYPE; DMD" Available at:http://omim.org/entry/310200?search=duchenne%20muscular%20dystrophy&highlight=duchenne%20dystrophy%20muscular. Last accessed 22/10/2015]
  3. [Online Mendelian Inheritance in Man (1966-2015) "MUSCULAR DYSTROPHY, DUCHENNE TYPE; DMD" Available at:http://omim.org/entry/310200?search=duchenne%20muscular%20dystrophy&highlight=duchenne%20dystrophy%20muscular. Last accessed 22/10/2015]

Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox