G1 Phase

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G1 phase, also known as the Gap 1 phase, is one of the stages within interphase. This stage of the cell cycle happens directly after mitosis and is a key point in which the decision is made as to whether another round of cell division will occur[1].

This stage can vary hugely in length as the cell will only enter the next stage in the cell cycle, S phase, if there are sufficient growth factor signals telling the cell to progress. Some cells that do not recieve all the necessary signals will move into the G0 phase, where they will remain until cell division is triggered by the prescence of cyclins. Other cells will enter terminal differentiation which means that they will not divide again and they have reached their most specific state. This is the case for many nerve cells[2].

During the G1 phase the cell grows and monitors both the internal and external environments to make sure that conditions are suitable for cell division to take place. This is because the cell is commited to another round of the cell cycle once the S phase begins[3].

References

  1. Alberts, B et al. (2016) Molecular Biology of the Cell (6th ed) New York: Garland Science: p. 963-970
  2. Hardin, J et al. (2012) Becker's World of the Cell (8th ed) San Francisco: Benjamin Cummings: p 549-551
  3. Alberts, B et al. (2016) Molecular Biology of the Cell (6th ed) New York: Garland Science: p. 963-970
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