Non-competitive inhibitor

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Michael-Menten Graph depicting effects of competitive and non-competitive enzyme inhibitors.
A non-competitive inhibitor binds to an enzyme in another place other than its active site. This results in a change in the structure of the enzyme so that it is no longer complementary to its substrate and therefore reduces its catalytic activity

The effects of a non-competitive inhibitor can be depicted by changes in its Michaelis-Menten graph[1]:

References

  1. Berg JM, Tymoczko JL, Gatto GJJ, Stayer L. Biochemistry. Eight Edition. New York: W. H. Freeman and Company; 2015
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