Nucleoplasm

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The protoplasm present in the nucleus of eukaryotic cells. It is a highly viscous liquid enveloped by the nuclear membrane, regulating the passage of molecules between the nucleoplasm and the cytoplasm[1]. It consists mainly of water, dissolved ions, and a complex mixture of other molecules. 32% of all human proteins have experimentally shown to be present within the nucleoplasm[2].

Function

The nucleoplasm acts as a suspension medium for components of the nucleus including the nucleolus, and chromatin. Nucleotides required for DNA replication and enzymes involved in other nuclear processes are also found dissolved within the nucleoplasm[3]. The nucleoplasm plays a role in the maintenance of the shape and structure of the nucleus[4]. The nuclear matrix is present within the nuclear hyaloplasm, the liquid component of the nucleoplasm[5].

References

  1. Del Mar College. Visual summary of Eukaryotic cells. 2016 [ cited 04/12/16] Available from: http://dmc122011.delmar.edu/nsci/biology/faculty/brower/powerLectures/ch4/chapter4_part2.pdf
  2. The Human Protein Atlas. The Human Cell: Nucleoplasm. 2016 [cited 04/12/16] Available from: http://www.proteinatlas.org/humancell/nucleoplasm
  3. Del Mar College. Visual summary of Eukaryotic cells. 2016 [ cited 04/12/16] Available from: http://dmc122011.delmar.edu/nsci/biology/faculty/brower/powerLectures/ch4/chapter4_part2.pdf
  4. Del Mar College. Visual summary of Eukaryotic cells. 2016 [ cited 04/12/16] Available from: http://dmc122011.delmar.edu/nsci/biology/faculty/brower/powerLectures/ch4/chapter4_part2.pdf
  5. UFRGS. Subcellular structures. 2016 [cited 04/12/16] Available from: http://www.ufrgs.br/imunovet/molecular_immunology/compartment.htm
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