Presynaptic cell

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The presynaptic cell exclusively contains neurotransmitters such as acetylcholine and glutamate, stored in vesicles. When an action potential arrives in the presynaptic cell, voltage gated Ca2+ channels open allowing for the influx of Ca2+ ions  down their concentration gradient, causing the vesicles to undergo exocytosis, emptying their contents into the synaptic cleft. These can the bind to receptors on the postsynaptic membrane[1].

References

  1. Neurosciust,The Synapse And The Presynaptic And Postsynaptic Terminals, Slideshow.net, 7th April 2009.
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