SRY Gene

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SRY.jpg
Known as the Sex Determining Region Y, the SRY Gene is located on the Y chromosome at the cytogenic location: Yp11.3.

Function

The SRY Gene induces male sex determination by producing a protein named the SRY protein. When activated, the SRY protein initiates the determination of unspecified cells into testes during embryonic development. This protein trigger produces a male phenotype and male hormones in mammals where the gene is active.

Health Conditions

Complications can arise with inheritence of the SRY Gene due to problems in mutations, insertions and deletions of the gene. Such inheritence patterns can lead to various health conditions such as:

References

  1. http://www.nature.com/scitable/content/18935/pierce_4_10_large_2.jpg
  2. http://ghr.nlm.nih.gov/gene/SRY
  3. http://embryo.asu.edu/pages/sex-determining-region-y-mammals
  4. http://dev.biologists.org/content/137/23/3921.full.pdf
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