As neuronal synapses are formed, they do not remain constant for life. Variation in electrical activity can lead to different rearrangements of the circuit connections. This means that synaptic transmission at a given synapse can change in response to a sensory input from an external source such as past experiences. Synaptic plasticity is simply the ability of a synapse to strengthen or weaken in response to frequent increases or decreases in activity, over a period of time. Long-Term Potentiation (LTP) is an example of synaptic plasticity. LTP is widely considered as one of the major cellular mechanisms that underlies our memory and learning abilities. Long Term Potentiation occurs when signal transmission across a synapse is increased in the long term due to repeated activity across a synapse in the short term.