Transmembrane domain

From The School of Biomedical Sciences Wiki
Jump to: navigation, search

Transmembrane domains are a protein's functional regions that are reaching over a phospholipid bilayer

Integral transmembrane proteins generally possess two or more transmembrane domains. These alternate between being intracellular and extracellular domains, arranged on either the inside or outside, respectively, of the membrane.

Amino acids on the transmembrane domains allow interaction with fatty acyl groups of membrane phospholipids. This allows anchoring of the protein in the membrane [1].

Reference

  1. Robert S. Hine (2008)fckLROxford Dictionary of Biology, Sixth Edition, New York: Oxford University Press. Page 654
Personal tools
Namespaces
Variants
Actions
Navigation
Toolbox