Transmembrane domains are a protein's functional regions that are reaching over a phospholipid bilayer.
Integral transmembrane proteins generally possess two or more transmembrane domains. These alternate between being intracellular and extracellular domains, arranged on either the inside or outside, respectively, of the membrane.
- ↑ Robert S. Hine (2008)fckLROxford Dictionary of Biology, Sixth Edition, New York: Oxford University Press. Page 654