1,4 glycosidic bond
Glycosidic bonds are formed due to a condensation reaction between two monosaccharides to form a polysaccharide. A condensation reaction is when two molecules combine to create a simple molecule and water is eliminated. The glycosidic bond can be hydrolysed by the addition of a water molecule.
The 1,4 glycosidic bond is formed between the carbon-1 of one monosaccharide and carbon-4 of the other. There are are two types - 1,4 alpha and 1,4 beta glycosidic bonds. 1,4 alpha glycosidic bonds are formed when the OH on the carbon-1 is below the glucose ring; while 1,4 beta glycosidic bonds are formed when the OH is above the plane[1][2]. When two alpha D-glucose, a more occurring isomer of glucose compared to the L-glucose, form a glycosidic linkage, the term is known as a α-1,4-glycosidic bond[3][4].
References
- ↑ Jeremy M. Berg, John L. Tymoczko, Lubert Stryer . Biochemistry Seventh Edition Freeman
- ↑ http://dictionary.reference.com/browse/Condensation_reaction - 29/11/2013
- ↑ Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 11.2, Complex Carbohydrates Are Formed by Linkage of Monosaccharides. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22396/
- ↑ Berg JM, Tymoczko JL, Stryer L. Biochemistry. 5th edition. New York: W H Freeman; 2002. Section 11.2, Complex Carbohydrates Are Formed by Linkage of Monosaccharides. Available from: http://www.ncbi.nlm.nih.gov/books/NBK22396/