TATA box

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The TATA box or the TATAAT is a consensus sequence located at the -10 position from the transcription start site of a promoter region in prokaryotes, and at approximately -25 to -35 in eukaryotes. This consensus sequence is important in transcription as TATA-box binding protein binds to the promoter sequence and recruits RNA Polymerase II to begin the synthesis of mRNA using the DNA template strand[1][2][3].

References

  1. Hartl D and Ruvolo M. 2012. Genetics Analysis Of Genes And Genomes. 8th edition. Chapter 10, Pages 352-353.
  2. Nature online - Available at: http://www.nature.com/scitable/definition/promoter-259 (Last accessed October 2016)
  3. https://www.nature.com/scitable/definition/tata-box-313 (last accessed 6th December 2018)