Aminoacyl: Difference between revisions

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Aminoacylation is the process of adding [[Amino acids|amino acids]] to&nbsp;[[TRNA|tRNA]] molecles during [[Translation|translation]] to form polypeptide chains. The reaction takes place in two steps and is catalysed by tRNA synthetase [[Enzyme|enzymes]]. First [[AMP|AMP]] is added to a [[Carboxyl group|carboxyl group]] on the amino acid forming an intermediate - amino acyl adenylate. The intermediate then&nbsp;reacts with uncharged tRNA to give amino acyl tRNA and AMP to be recycled and reused again. This results in the basis of protein translation.&nbsp;<ref>Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts and Peter Walter, 2008, Molecular Biolofy of the Cell, 5th edition, Published by Garland Science, New York</ref>
Aminoacylation is the process of adding [[Amino acids|amino acids]] to[[TRNA|tRNA]] molecles during [[Translation|translation]] to form polypeptide chains. The reaction takes place in two steps and is catalysed by tRNA synthetase [[Enzyme|enzymes]]. First [[AMP|AMP]] is added to a [[Carboxyl group|carboxyl group]] on the amino acid forming an intermediate - amino acyl adenylate. The intermediate then&nbsp;reacts with uncharged tRNA to give amino acyl tRNA and AMP to be recycled and reused again. This results in the basis of protein translation.&nbsp;<ref>Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts and Peter Walter, 2008, Molecular Biolofy of the Cell, 5th edition, Published by Garland Science, New York</ref>&nbsp;
 
=== References ===
 
<references /> &nbsp;

Latest revision as of 23:39, 26 November 2014

Aminoacylation is the process of adding amino acids to tRNA molecles during translation to form polypeptide chains. The reaction takes place in two steps and is catalysed by tRNA synthetase enzymes. First AMP is added to a carboxyl group on the amino acid forming an intermediate - amino acyl adenylate. The intermediate then reacts with uncharged tRNA to give amino acyl tRNA and AMP to be recycled and reused again. This results in the basis of protein translation. [1]

References

  1. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts and Peter Walter, 2008, Molecular Biolofy of the Cell, 5th edition, Published by Garland Science, New York