Aminoacyl

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Aminoacylation is the process of adding amino acids to tRNA molecles during translation to form polypeptide chains. The reaction takes place in two steps and is catalysed by tRNA synthetase enzymes. First AMP is added to a carboxyl group on the amino acid forming an intermediate - amino acyl adenylate. The intermediate then reacts with uncharged tRNA to give amino acyl tRNA and AMP to be recycled and reused again. This results in the basis of protein translation. [1]

References

  1. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts and Peter Walter, 2008, Molecular Biolofy of the Cell, 5th edition, Published by Garland Science, New York
 
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