Glycerine: Difference between revisions

From The School of Biomedical Sciences Wiki
Jump to navigation Jump to search
Created page with "Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, oudourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low tox..."
 
Nnjm2 (talk | contribs)
Cleaned up the text.
 
(4 intermediate revisions by 3 users not shown)
Line 1: Line 1:
Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, oudourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity it is ideal for cough syrups and other medicines.
Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, odourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity, it is ideal for cough syrups and other medicines.  


=== Structure  ===


Glycerol contains 3 [[Hydroxyl group|hydroxyl groups]], which make it [[Water|water]] soluble.


STURUCTURE
Its molecular formula is CH2(OH)CH(OH)CH2OH


Glycerol contains 3 hydroxyl groups, these make it water soluble.
=== Production  ===


It's molecular formula is CH2(OH)CH(OH)CH2OH
Glycerol is mainly produced as a byproduct in other processes, such as saponification of fats (soap making), as [[Glycerol|glycerol]] forms the core of [[Triglycerides|triglycerides]].
 
It is also produced as a by-product in biodiesel production.
 
=== Metabolism  ===
 
Gluconeogenisis occurs in the [[Liver|liver]], and is when the body uses [[Glycerol|glycerol]] to make [[Glucose|glucose]] in fasting conditions.
 
Glycerol is one of the 3 main carbon sources in the body for [[Gluconeogenesis|gluconeogenesis]]. The glycerol is released from the adipose stores of [[Triacylglycerol|triacylglycerol]] and [[Phosphorylation|phosphorylated]] into [[Glycerol-3-P|glycerol-3-P]]. Glycerol-3-P is then converted to [[Dihydroxyacetone-P|dihydroxyacetone-P]], which then produces [[Glucose|glucose]]<ref>Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.</ref>.
 
=== References  ===
 
<references />

Latest revision as of 20:02, 4 December 2017

Glycerine (also known as Glycerol or Glycerin) is a colourless, viscous, odourless fluid that is mainly used in pharmaceutical companies. Due to its sweet taste and low toxicity, it is ideal for cough syrups and other medicines.

Structure

Glycerol contains 3 hydroxyl groups, which make it water soluble.

Its molecular formula is CH2(OH)CH(OH)CH2OH

Production

Glycerol is mainly produced as a byproduct in other processes, such as saponification of fats (soap making), as glycerol forms the core of triglycerides.

It is also produced as a by-product in biodiesel production.

Metabolism

Gluconeogenisis occurs in the liver, and is when the body uses glycerol to make glucose in fasting conditions.

Glycerol is one of the 3 main carbon sources in the body for gluconeogenesis. The glycerol is released from the adipose stores of triacylglycerol and phosphorylated into glycerol-3-P. Glycerol-3-P is then converted to dihydroxyacetone-P, which then produces glucose[1].

References

  1. Marks, L., Marks' Basic Medical Biochemistry A Clinical Approach, 4th Edition, page 562.