Point mutation: Difference between revisions
Jump to navigation
Jump to search
Created page with " A point mutation refers to a substitution of a single base nucleotide in a sequence of DNA or RNA. The effects of this may be [[Silent mutation|silen..." |
(No difference)
|
Revision as of 22:42, 8 November 2013
A point mutation refers to a substitution of a single base nucleotide in a sequence of DNA or RNA. The effects of this may be silent (in which after the substitution, the sequence still codes for the same amino acid due to the genetic code being degenerate), nonsense (the substitution leads to the sequence coding for a stop codon) or missense (the substitution leads to the sequence coding for a different amino acid which may have similar or different properties and alter the functionality of the polypeptide).[1]
References
- ↑ Ghr.nlm.nih.gov. 2013. Point mutation - Glossary Entry - Genetics Home Reference. [online] Available at: http://ghr.nlm.nih.gov/glossary=pointmutation [Accessed: 8 Nov 2013].