AB blood group: Difference between revisions

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The AB blood group is displayed in individuals who's red blood cells display both the A and B antigen. This is a rare blood group type, AB negative being the rarest.<ref>Dean L. Bethesda, blood groups and red cell antigens, 2005,5 [https://www.ncbi.nlm.nih.gov/books/NBK2267/]</ref>.  
The AB [[Blood|blood]] group is displayed in individuals whose [[Red blood cells|red blood cells]] display both the [[A antigen|A]] and [[B antigen|B antigen]]. This is a rare blood group type, [[AB negative|AB negative]] being the rarest<ref>Dean L. Bethesda, blood groups and red cell antigens, 2005,5 [https://www.ncbi.nlm.nih.gov/books/NBK2267/]</ref>.  


The ABO gene encodes for the formation of glycosyltransferases that add N-acetylgalactosamine and galactose to the H antigen already present on the red blood cells, to form both A and B antigens<ref>Victor A. McKusick,ABO GLYCOSYLTRANSFERASE; ABO , 1986,OMIM entry description. [https://omim.org/entry/110300]</ref>.  
The ABO gene encodes for the formation of [[glycosyltransferases|glycosyltransferases]] that add [[N-acetylgalactosamine|N-acetylgalactosamine]] and [[Galactose|galactose]] to the [[H antigen|H antigen]] already present on the red blood cells, to form both A and B [[antigen|antigens]]<ref>Victor A. McKusick,ABO GLYCOSYLTRANSFERASE; ABO , 1986,OMIM entry description. [https://omim.org/entry/110300]</ref>.  


The individual with the AB blood type does not contain any antibodies against A and B antigens. This is so the immune system does not attack the red blood cells<ref>Marius Lixandru, What are blood types and what do they mean?, Natureworld, 2008 [https://www.natureword.com/tag/blood-types-antigens-and-antibodies/]</ref>.  
The individual with the AB blood type does not contain any [[antibodies|antibodies]] against A and B antigens. This is so the [[immune system|immune system]] does not attack the red blood cells<ref>Marius Lixandru, What are blood types and what do they mean?, Natureworld, 2008 [https://www.natureword.com/tag/blood-types-antigens-and-antibodies/]</ref>.  


=== References  ===
=== References  ===


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Latest revision as of 10:36, 18 October 2018

The AB blood group is displayed in individuals whose red blood cells display both the A and B antigen. This is a rare blood group type, AB negative being the rarest[1].

The ABO gene encodes for the formation of glycosyltransferases that add N-acetylgalactosamine and galactose to the H antigen already present on the red blood cells, to form both A and B antigens[2].

The individual with the AB blood type does not contain any antibodies against A and B antigens. This is so the immune system does not attack the red blood cells[3].

References

  1. Dean L. Bethesda, blood groups and red cell antigens, 2005,5 [1]
  2. Victor A. McKusick,ABO GLYCOSYLTRANSFERASE; ABO , 1986,OMIM entry description. [2]
  3. Marius Lixandru, What are blood types and what do they mean?, Natureworld, 2008 [3]